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In a study published in the journal Science Translational Psychiatry, researchers found that sildenafil, the active ingredient in Viagra, was significantly more potent at increasing sexual arousal than placebo in rats, with effects lasting up to 3 hours after administration. Sildenafil (25 mg) increased sEPSC-1 P levels in the rats by a mean of 5.5%. Sildenafil’s therapeutic effects are comparable with that of tadalafil (5 mg).
This is the first study that demonstrates the drug’s ability to increase sexual arousal in male rats. Sildenafil is a phosphodiesterase type 5 inhibitor, which helps to relax penile arteries, thereby increasing blood flow. In rats, the drug increases penile blood flow by an approximate 5-fold after 4 hours. This effect lasts for up to 6 hours, providing a window of opportunity for sexual stimulation.
This research is the first study to show that sildenafil, the active ingredient in Viagra, is more potent than placebo at increasing sexual arousal. Sildenafil is a selective and reversible inhibitor of cyclic guanosine monophosphate (cGMP), which is a central nervous system (CNS) in the central nervous system and acts to relax smooth muscle, nerves, and blood vessels in the genital area.
Sildenafil (25 mg) is a phosphodiesterase type 5 inhibitor that helps to relax penile arteries, which can increase sexual arousal. Sildenafil increases penile blood flow by a similar amount as placebo by approximately 5-fold after 4 hours.
In a double-blind, placebo-controlled clinical study, male rats that received Viagra (25 mg) and placebo received intracavernous injection of sildenafil 5 mg or placebo twice weekly for 4 weeks. Paired-in randomized controlled trials were conducted to test the efficacy of Viagra on the sexual and overall physiological measures of sexual arousal, and on the sexual and psychological aspects of sexual response.
Sildenafil is a phosphodiesterase type 5 inhibitor that helps to relax penile arteries, which can increase sexual arousal. Sildenafil increases penile blood flow by an approximate 5-fold after 4 hours.
This is the first study to show that sildenafil, the active ingredient in Viagra, is more potent than placebo at increasing sexual arousal.
In a double-blind, placebo-controlled clinical study, male rats that received Viagra and placebo received intracavernous injection of sildenafil 5 mg or placebo twice weekly for 4 weeks.
The study shows that sildenafil is more potent than placebo at increasing sexual arousal, which is not consistent with its effects on sexual arousal.
Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.
Product Product SpecificationUK Pharmacy: 25mg, 50mg, 100mg.
How is Sildenafil taken?Treatment is usually stops working in about 30 minutes.
What are the common side effects?Common side effects:
What is Erectile Dysfunction (ED)?ED is a condition in which the ability to get and maintain an erection firm enough for sexual activity. Sildenafil is usually prescribed in 25mg, 50mg, 100mg strengths.
Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.
Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.
esar de acceder a menus es especialmente de los mecanism Sildenafil, se pueden diferenciar las dosis de Sildenafil en esta producta puede ayudar a menus ese mecanism.The list includes prescription Sildenafil, over-the-counter Sildenafil products, and natural medications. Always consult a doctor for a prescription.
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